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KMID : 0363219960340060961
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Korean Journal of Dermatology
1996 Volume.34 No. 6 p.961 ~ p.967
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Treatment of Ota's Nevus with the Alexandrite Laser
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Abstract
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Background :
@EN Recently, Q-switched lasers have been reported to be sucessful in treating Ota's nevus without scarring. Utilizing the principle of selective photothermolysis, the Alexandrite laser has been developed for dermal pigmented lesions and tattoos.
@ES Objective :
@EN In this study, we evaluated the clinical, histopathological and ultrastructual effect of the Alexandrite laser in the treatment of Nevus of Ota.
@ES Methods :
@EN Forty-seven patients with nevus of Ota were treated with energy densites ranging from 5.0 to 8.0 J/cm2 at a minimum of 6 week intervals. Sequential skin biopsy specimens were processed for the light microscope with H&Eand Fontana-Masson
stains
and
the electron microscope.
@ES Results :
@EN The average number of treatments were 2.8 per patient. After two treatment sessions, 93% patients 26 to 75% improvement was seen. After three treatments 50 to 95% improvement was seen. No patients had permanent textual changes or scarring. On
light
microscop most of the dendritic melanocytes in the upper dermis were not observed in biopsy specimens taken after clinical improvement. Electron microscopy revealed damaged melanosomes in the upper dermis immediately after irradiation.
@ES Conclusion :
@EN Treatment with the Alexandrite laser for nevus of Ota is considered to be a safe and effective method. (Kor J Dermatol 1996;34(6) : 9612~967)
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KEYWORD
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